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Preliminary testing of a new pain-free Fibromyalgia drug showing positive results

A recent article published on March 20th, 2012 by ME/CFS Australia (SA) released news of the discovery of an enzyme in the brain that is responsible for pain-memory. With this enzyme, called PKMzeta, researchers on the study are hoping to develop a marketable drug to block its ability to make long-term memory storage of pain in the brain to help Fibromyalgia patients live pain-free. As the researchers state, pain-memory often intensifies pain for the future incidents of injury to the same part of the body, and can at times lead to hyper-sensitivity. The current tests of blocking this enzyme on rats have displayed the following:

  • The PKMzeta enzyme is responsible for pain-memory that can lead to pain intensification and hypersensitivity
  • Rats that were treated against the functioning of this enzyme reversed the pain processing abnormality in the spinal cord dorsal horn and hypersensitivity across the skin

Lesson of the article: new pain-free Fibromyalgia drugs are in the preliminary stages of testing and are displaying positive results



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